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Zhdanova O, Srivastava S, Di L, Li Z, Tchelebi L, Dworkin S, Johnstone DB, Zavadil J, Chong MM, Littman DR, Holzman LB, Barisoni L, Skolnik EY. The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy . Kidney Int. 2011 Oct;80(7):719-30. Epub 2011 May 4. PMID: 21544061.
Podocytes from Drosha and Dicer mutants have decreased expression of synaptopodin and Wilms' tumor-1 (WT-1).
Immunohistochemistry of histological sections from 4- to 5-week-old wild-type (WT), Drosha, and Dicer mutants immunostained with antibodies to synaptopodin and WT-1. Podocyte expression of synaptopodin and WT-1 are decreased in both Drosha and Dicer mutants.