This Core is partially supported by the NYU Cancer Institute Center Support Grant, 5P30CA0016087-32. Please remember to acknowledge the Cancer Center in publications and all forms of media related to a Cancer Center supported study.
For the Cancer Center the following manuscript citation is suggested:"Supported in part by grant 5P30CA016087-32 from the National Cancer Institute."
The mission of the new NYU Medical School Proteomics Core is to assist the research community with the characterization of proteins from a wide range of biological experiments (SDS-PAGE, immuno isolations, whole cell extracts, etc.) by offering access to unique scientific expertise for protein mass spectrometry. The focus of the center is comprehensive characterization of complex protein samples, mapping of post translational modifications, quantitative analysis of priotein expression (label and label free) using "bottom up" and "top down" approaches.
The laboratory occupies newly renovated space in MSB 301/302 and shares the floor with the Genomics Core creating a nexus for "omics" technology. The fully integrated Genomics and Proteomics Resource Laboratories will offer bioinformatics and data management support. In addition, the Proteomics Resource Center provides detailed consulting in proteomic experimental design prior to sample production and mass spectrometric analysis to ensure the best possible outcome of any experiment. The laboratory is equipped with state-of-the-art high-resolution mass spectrometric instrumentation offering three different types of dissociation techniques for peptide sequencing.
The Proteomics Core, directed by Dr. Beatrix Ueberheide offers:
- Protein identification
- Mapping of post translational modifications
- Comprehensive characterization of complex protein samples
- Protein quantification (label and label free)
- Intact protein mass detection