2011 Archive

• Acehan D, Malhotra A, Xu Y, Ren M, Stokes DL, Schlame M.Cardiolipin affects the supramolecular organization of ATP synthase in mitochondria. Biophys J. 2011 May 4;100(9):2184-92. PMID: 21539786.
• Allen GS, Wu CC, Cardozo T, Stokes DL. The Architecture of CopA from Archeaoglobus fulgidus Studied by Cryo-Electron Microscopy and Computational Docking. Structure. 2011 Sep 7;19(9):1219-32. Epub 2011 Aug 4. PMID: 21820315.
• Asp P, Blum R, Vethantham V, Parisi F, Micsinai M, Cheng J, Bowman C, Kluger Y, Dynlacht BD. PNAS Plus: Genome-wide remodeling of the epigenetic landscape during myogenic differentiation. Proc Natl Acad Sci U S A. May 31 2011;108(22):E149-158. PMID: 21551099.
• Breart B, Ramos-Perez WD, Mendoza A, Salous AK, Gobert M, Huang Y, Adams RH, Lafaille JJ, Escalante-Alcalde D, Morris AJ, Schwab SR. Lipid phosphate phosphatase 3 enables efficient thymic egress. J Exp Med. May 16 2011. PMID: 21576386.
• Cai T, Li X, Ding J, Luo W, Li J, Huang C. A Cross-Talk Between NFAT and NF-kappaB Pathways is Crucial for Nickel-Induced COX-2 Expression in Beas-2B Cells. Curr Cancer Drug Targets. Jun 1 2011;11(5):548-559. PMID: 21486220.
• Cazettes F, Cohen JI, Yau PL, Talbot H, Convit A. Obesity-mediated inflammation may damage the brain circuit that regulates foodintake. Brain Res. 2011 Feb 10;1373:101-9. PMID: 21146506.
• Cimmino L, Abdel-Wahab O, Levine RL, Aifantis I. TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation. Cell Stem Cell. 2011 Sep 2;9(3):193-204. PMID: 21885017.
• Collins A, Hewitt SL, Chaumeil J, Sellars M, Micsinai M, Allinne J, Parisi F, Nora EP, Bolland DJ, Corcoran AE, Kluger Y, Bosselut R, Ellmeier W, Chong MM, Littman DR, Skok JA. RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation. Immunity. Mar 25 2011;34(3):303-314. PMID: 21435585.
• Colnaghi L, Jones MJ, Cotto-Rios XM, Schindler D, Hanenberg H, Huang TT. Patient-derived C-terminal mutation of FANCI causes protein mislocalization and reveals putative EDGE motif function in DNA repair. Blood. 117(7): 2247-56. Feb 17 2011. PMID: 20971953.
• Connolly MK, Ayo D, Malhotra A, Hackman M, Bedrosian AS, Ibrahim J, Cieza-Rubio NE, Nguyen AH, Henning JR, Dorvil-Castro M, Pachter HL, Miller G. Dendritic cell depletion exacerbates acetaminophen hepatotoxicity. Hepatology. May 13 2011. PMID: 21574173.
• Cotto-Rios XM, Jones MJ, Busino L, Pagano M, Huang TT. APC/CCdh1-dependent proteolysis of USP1 regulates the response to UV-mediated DNA damage. J Cell Biol. 2011 Jul 25;194(2):177-86. Epub 2011 Jul 18. PMID: 21768287.
• Darvishian, F., Singh, B., Krauter, S., et al. Impact of Decalcification on Receptor Status in Breast Cancer. Breast J. 2011 Nov;17(6):689-91. doi: 10.1111/j.1524-4741.2011.01168.x. Epub 2011 Oct 17. PMID: 21999708.
• Deriano L, Chaumeil J, Coussens M, Multani A, Chou Y, Alekseyenko AV, Chang S, Skok JA, Roth DB. The RAG2 C terminus suppresses genomic instability and lymphomagenesis. Nature. Mar 3 2011;471(7336):119-123. PMID: 21368836.
• Gaziel-Sovran A, Segura MF, Di Micco R, Collins MK, Hanniford D, Vega-Saenz de Miera E, Rakus JF, Dankert JF, Shang S, Kerbel RS, Bhardwaj N, Shao Y, Darvishian F, Zavadil J, Erlebacher A, Mahal LK, Osman I, Hernando E. miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis. Cancer Cell. 2011 Jul 12;20(1):104-18. PMID: 21741600.
• Godefroy E, Manches O, Dreno B, Hochman T, Rolnitzky L, Labarriere N, Guilloux Y, Goldberg J, Jotereau F, Bhardwaj N. Matrix Metalloproteinase-2 Conditions Human Dendritic Cells to Prime Inflammatory T(H)2 Cells via an IL-12- and OX40L-Dependent Pathway. Cancer Cell. Mar 8 2011;19(3):333-346. PMID: 21397857.
• Gupta R, Babb JS, Singh B, Chiriboga L, Liebes L, Adams S, Demaria S. The Numbers of FoxP3+ Lymphocytes in Sentinel Lymph Nodes of Breast Cancer Patients Correlate With Primary Tumor Size but Not Nodal Status. Cancer Invest. Jul 2011;29(6):419-425. PMID: 21649468.
• Gupta R, Babb JS, Singh B, Chiriboga L, Liebes L, Adams S, Demaria S. The Numbers of FoxP3+ Lymphocytes in Sentinel Lymph Nodes of Breast Cancer Patients Correlate With Primary Tumor Size but Not Nodal Status. Cancer Invest. Jul 2011;29(6):419-425. PMID: 21649468.
• Gupta, R., J. S. Babb, et al. The Numbers of FoxP3+ Lymphocytes in Sentinel Lymph Nodes of Breast Cancer Patients Correlate With Primary Tumor Size but Not Nodal Status. Cancer Invest. 2011 Jul;29(6):419-25. PMID: 21649468.
• Huynh C, Segura MF, Gaziel-Sovran A, Menendez S, Darvishian F, Chiriboga L, Levin B, Meruelo D, Osman I, Zavadil J, Marcusson EG, Hernando E. Efficient in vivo microRNA targeting of liver metastasis. Oncogene. Mar 24 2011;30(12):1481-1488. PMID: 21102518
• Jimenez-Baranda S, Greenbaum B, Manches O, Handler J, Rabadan R, Levine A, Bhardwaj N. Oligonucleotide Motifs That Disappear during the Evolution of Influenza Virus in Humans Increase Alpha Interferon Secretion by Plasmacytoid Dendritic Cells. J Virol. Apr 2011;85(8):3893-3904. PMID: 21307198.
• Kang SS, Herz J, Kim JV, Nayak D, Stewart-Hutchinson P, Dustin ML, McGavern DB. Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection. J Exp Med. 2011 Apr 11;208(4):747-59. PMID: 21464219.
• Klinakis A, Lobry C, Abdel-Wahab O, Oh P, Haeno H, Buonamici S, van De Walle I, Cathelin S, Trimarchi T, Araldi E, Liu C, Ibrahim S, Beran M, Zavadil J, Efstratiadis A, Taghon T, Michor F, Levine RL, Aifantis I. A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia. Nature. 2011 May 12;473(7346):230-3. PMID: 21562564.
• Leo-Macias A, Katz G, Wei H, Alimova A, Katz A, Rice WJ, Diaz-Avalos R, Hu GB, Stokes DL, Gottlieb P. Toroidal surface complexes of bacteriophage 12 are responsible for host-cell attachment. Virology. 2011 Jun 5;414(2):103-9. Epub 2011 Apr 13. PMID: 21489589.
• Levis WR, MD, Rose-Paraskevas L, MD, Jacobson M, Spencer J, Spencer T, RN, MPH, Martiniuk F. Endemic leprosy in New York City. Arch Derm 147:624-626, 2011. PMID: 21576589.
• Liu J, Zhang D, Luo W, Yu Y, Yu J, Li J, Zhang X, Zhang B, Chen J, Wu XR, Rosas-Acosta G, Huang C. The X-linked inhibitor of apoptosis protein (XIAP) mediates cancer cell motility Via RhoGDP dissociation inhibitor (RhoGDI)-dependent regulation of cytoskeleton. J Biol Chem. Mar 14 2011. PMID: 21402697.
• Loudin MG, Wang J, Eastwood Leung HC, Gurusiddappa S, Meyer J, Condos G, Morrison D, Tsimelzon A, Devidas M, Heerema NA, Carroll AJ, Plon SE, Hunger SP, Basso G, Pession A, Bhojwani D, Carroll WL, Rabin KR. Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles. Leukemia. Jun 7 2011. PMID: 21647151.
• McCloskey ML, Curotto de Lafaille MA, Carroll MC, Erlebacher A. Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cells. J Exp Med. Jan 17 2011;208(1):135-148. PMID: 21173103.
• Mita P, Savas JN, Djouder N, Yates JR, 3rd, Ha S, Ruoff R, Schafler ED, Nwachukwu JC, Tanese N, Cowan NJ, Zavadil J, Garabedian MJ, Logan SK. Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP. Mol Cell Biol. Jul 5 2011. PMID: 21730289.
• Moran-Crusio K, Reavie L, Shih A, Abdel-Wahab O, Ndiaye-Lobry D, Lobry C, Figueroa ME, Vasanthakumar A, Patel J, Zhao X, Perna F, Pandey S, Madzo J, Song C, Dai Q, He C, Ibrahim S, Beran M, Zavadil J, Nimer SD, Melnick A, Godley LA, Aifantis I, Levine RL. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell. 2011 Jul 12;20(1):11-24. Epub 2011 Jun 30. PMID: 21723200.
• Morrison DJ, Hogan LE, Condos G, Germino N, Moskowitz NP, Lee L, Bhojwani D, Horton TM, Belitskaya-Levy I, Sapra P, Greenberger L, Grupp SA, Teachey DT, Raetz EA, Carroll WL. Endogenous Knock-Down of Survivin Improves Chemotherapeutic Response in ALL Models. Leukemia. 2011 Aug 16. doi: 10.1038/leu.2011.199. [Epub ahead of print]. PMID: 21844871.
• Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, George-Hyslop PS, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, Decarli C, Dekosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Gen 43:436-41, 2011. PMID: 21460841.
• Nans A, Einheber S, Salzer JL, Stokes DL. Electron tomography of paranodal septate-like junctions and the associated axonal and glial cytoskeletons in the central nervous system. J Neurosci Res. 2011 Mar;89(3):310-9. doi: 10.1002/jnr.22561. Epub 2010 Dec 29. PMID: 21259318.
• Nardiello T, Jungbluth AA, Mei A, Diliberto M, Huang X, Dabrowski A, Andrade VC, Wasserstrum R, Ely S, Niesvizky R, Pearse R, Coleman M, Jayabalan DS, Bhardwaj N, Old LJ, Chen-Kiang S, Cho HJ. MAGE-A inhibits apoptosis in proliferating myeloma cells through repression of Bax and maintenance of survivin. Clin Cancer Res. May 12 2011. PMID: 21565982.
• Nguyen DH, Oketch-Rabah HA, Illa-Bochaca I, Geyer FC, Reis-Filho JS, Mao JH, Ravani SA, Zavadil J, Borowsky AD, Jerry DJ, Dunphy KA, Seo JH, Haslam S, Medina D, Barcellos-Hoff MH. Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Cancer Latency and Affect Tumor Type. Cancer cell. May 17 2011;19(5):640-651. PMID: 21575864.
• Nierenberg J,Sidtis J, Martiniuk F, Blennow K, Pomara N, and Mehtaph P. TOMM40 poly-T variants and cerebrospinal fluid amyloid beta in the elderly. Neurochemical Research 36:1124-1128, 2011. PMID: 21455713.
• O'Brien M, Manches O, Sabado RL, Jimenez Baranda S, Wang Y, Marie I, Rolnitzky L, Markowitz M, Margolis DM, Levy D, Bhardwaj N. Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently INF- α-producing and partially matured phenotype. J Clin Invest. 121(3): 1088-101. Mar 1 2011. PMID: 21339641.
• Ornelas C, Lodescar R, Durandin A, Canary JW, Pennell R, Liebes LF, Weck M. Combining aminocyanine dyes with polyamide dendrons: a promising strategy for imaging in the near-infrared region. Chemistry. Mar 21 2011;17(13):3619-362. PMID: 21337432.
• Ornelas C, Pennell R, Liebes LF, Weck M. Construction of a well-defined multifunctional dendrimer for theranostics. Org Lett. Mar 4 2011;13(5):976-979. PMID: 21291239.
• Osei-Sarfo K, Martello L, Ibrahim S, Pellicer A. The human Rgr oncogene is overexpressed in T-cell malignancies and induces transformation by acting as a GEF for Ras and Ral. Oncogene. Mar 28 2011. PMID: 21441953.
• Rabbani P, Takeo M, Chou W, Myung P, Bosenberg M, Chin L, Taketo MM, Ito M. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration. Cell. 145(6): 941-955. June 10, 2011. PMID: 21663796.
• Rose AE, Poliseno L, Wang J, Clark M, Pearlman A, Wang G, Vega YS, Medicherla R, Christos PJ, Shapiro R, Pavlick A, Darvishian F, Zavadil J, Polsky D, Hernando E, Ostrer H, Osman I. Integrative genomics identifies molecular alterations that challenge the linear model of melanomaprogression. Cancer Res. Apr 1 2011;71(7):2561-2571. PMID: 21343389.
• Schwickert TA, Victora GD, Fooksman DR, Kamphorst AO, Mugnier MR, Gitlin AD, Dustin ML, Nussenzweig MC. A dynamic T cell-limited checkpoint regulates affinity-dependent B cell entry into the germinal center. J Exp Med. 2011 Jun 6;208(6):1243-52. PMID: 21576382.
• Sczesnak A, Segata N, Qin X, Gevers D, Petrosino JF, Huttenhower C, Littman DR, Ivanov II. The Genome of Th17 Cell-Inducing Segmented Filamentous Bacteria Reveals Extensive Auxotrophy and Adaptations to the Intestinal Environment. Cell Host and Microbe: 10 (3): 260-272, 2011. PMID: 21925113.
• Siev M, Yu X, Prados-Rosales R, Martiniuk FT, Casadevall A, Achkar JM. Correlation between serum and plasma antibody titers to mycobacterial antigens. Clin Vaccine Immunol. 2011 Jan;18(1):173-5. Epub 2010 Nov 3. PMID: 21047999.
• Smith ME, Cimica V, Chinni S, Jana S, Koba W, Yang Z, Fine E, Zagzag D, Montagna C, Kalpana GV. Therapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1. Proc Natl Acad Sci U S A. Jan 4 2011;108(1):319-324. PMID: 21173237.
• Tagliani, E., Chao, S., Nancy, P., Tay, C.S., Pamer, E.G. and Erlebacher, A. 2011. Coordinate regulation of tissue macrophage and dendritic cell population dynamics by CSF-1. J Exp Med. 2011 Aug 29;208(9):1901-16. Epub 2011 Aug 8. PMID: 21825019.
• Tchou-Wong KM, Kiok K, Tang Z, Kluz T, Arita A, Smith PR, Brown S, Costa M. Effects of Nickel Treatment on H3K4 Trimethylation and Gene Expression. PLoS One. 2011;6(3):e17728. PMCID: 21455298.
• Tu TJ, Ma MW, Monni S, Rose AE, Yee H, Darvishian F, Polsky D, Berman RS, Shapiro RL, Pavlick AC, Mazumdar M, Osman I. A High Proliferative Index of Recurrent Melanoma Is Associated with Worse Survival. Oncology. Jun 24 2011;80(3-4):181-187. PMID: 21701232.
• Waite JC, Leiner I, Lauer P, Rae CS, Barbet G, Zheng H, Portnoy DA, Pamer EG, Dustin ML. Dynamic imaging of the effector immune response to listeria infection in vivo. PLoS Pathog. 2011, 7(3):e1001326. PMID: 21455492.
• Wang D, Zavadil J, Martin L, Parisi F, Friedman E, Levy D, Harding H, Ron D, and Gardner, L. Inhibition of nonsense mediated RNA decay by the tumor microenvironment promotes tumorigenesis. Mol Cell Biol. 2011 Sep;31(17):3670-80. Epub 2011 Jul 5. PMID: 21730287.
• Wang J, Zhang W, Nardi MA, Li Z. HIV-1 Tat induced-platelet activation and release of CD154 contribute to HIV-1 associated autoimmune thrombocytopenia. J Thromb Haemost. 2011 Mar;9(3):562-73. PMID: 21143381.
• Wang, J., Yi, Z., Wang, S., and Li, Z. The effect of decitabine on megakaryocyte maturation and platelet release. Thrombosis and Haemostasis. Thromb Haemost. 2011 Aug;106(2):337-43. Epub 2011 Jun 28. PMID: 21713321.
• Wei JJ, Wu X, Peng Y, Shi G, Olca B, Yang X, Daniels G, Osman I, Ouyang J, Hernando E, Pellicer A, Rhim JS, Melamed J, Lee P. Regulation of HMGA1 Expression by MicroRNA-296 Affects Prostate Cancer Growth and Invasion. Clin Cancer Res. Mar 15 2011;17(6):1297-1305. PMID: 21138859.
• Wu J, Liu Z, Shao C, Gong Y, Hernando E, Lee P, Narita M, Muller W, Liu J, Wei JJ. HMGA2 Overexpression-Induced Ovarian Surface Epithelial Transformation Is Mediated Through Regulation of EMT Genes. Cancer Res. Jan 15 2011;71(2):349-359. PMID: 21224353.
• Wu X, Xu K, Zhang L, Deng Y, Lee P, Shapiro E, Monaco M, Makarenkova HP, Li J, Lepor H, Grishina I. Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism. Dev Biol. 15;356(2):337-49. Aug. 2011. PMID: 21624358.
• Yuan Y, Cohen DJ, Love E, Yaw M, Levinson B, Nicol SJ, Hochster HS. Phase I dose-escalating study of biweekly fixed-dose rate gemcitabine plus pemetrexed in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2011 Aug;68(2):371-8. Epub 2010 Oct 27. PMID: 20978761.
• Zamparini AL, Davis MY, Malone CD, Vieira E, Zavadil J, Sachidanandam R, Hannon GJ, Lehmann R. Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila. Development. 2011 Sep;138(18):4039-50. PMID: 21831924.
• Zhdanova O, Srivastava S, Di L, Li Z, Tchelebi L, Dworkin S, Johnstone DB, Zavadil J, Chong MM, Littman DR, Holzman LB, Barisoni L, Skolnik EY. The inducible deletion of Drosha and microRNAs in mature podocytes results in a collapsing glomerulopathy.Kidney Int. 2011 Oct;80(7):719-30. Epub 2011 May 4. PMID: 21544061.